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CRYSTALLINE FORMS OF 5-BROMO-2,6-DI(1 H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE AND NEW SALTS
CRYSTALLINE FORMS OF 5-BROMO-2,6-DI(1 H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE AND NEW SALTS
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机译:5-溴2,6-二(1 H I>-吡唑-1-基)嘧啶-4-胺和新盐的晶体形式
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摘要
This application relates to various crystalline forms of 5-bromo-2,6-di(1H-pyrazol-1- yl)pyrimidin-4-amine and salt thereof, as well as compositions and methods of using the same. In some embodiments the crystalline forms also contain water ("hydrates"). These materials are useful in the treatment of various diseases, including carcinomas, specifically lung cancer and more specifically non-small cell lung cancer.
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机译:本申请涉及5-溴-2,6-二(1′I> H I>-吡唑-1-基)嘧啶-4-胺及其盐的各种晶体形式,以及其组合物和方法。使用相同的。在一些实施方案中,结晶形式还包含水(“水合物”)。这些材料可用于治疗各种疾病,包括癌症,特别是肺癌,更特别是非小细胞肺癌。
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