TUNABLE PROBES FOR SELECTIVE PROTEIN LABELLING AND ENZYME INHIBITION

摘要

The present invention relates to methods of selectively reacting a compound of Formula (I) with a cysteine residue, which is contained in the sequence of a polypeptide. The methods may be employed in the fields of labelling polypeptides, detecting polypeptides, modulation of enzyme activity, isolation of polypeptides, methods of diagnostics, methods of prevention or treatment of clinical conditions or methods of transportation of compounds e.g. prodrugs.