The present invention relates to topical pharmaceutical compositions of cyclosporine A comprising at least a volatile alcohol, 2-(2-ethoxyethoxy)ethanol, a surfactant or surfactant mixture having an HLB value from 10 to 18, and a non-volatile organic solvent other than 2-(2-ethoxyethoxy)ethanol, the surfactants having an HLB value from 10 to 18 and triacetin. The invention also relates to a process for the preparation of said compositions and to their use in the prevention and/or treatment of several diseases, particularly psoriasis and atopic dermatitis.
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