METHOD OF PREPARING BIOACTIVE SUBSTANCE-ENCAPSULATED ETHOSOME, ETHOSOME COMPOSITION, AND COSMETIC COMPOSITION INCLUDING ETHOSOME COMPOSITION

摘要

Provided is a method of preparing a bioactive substance-encapsulatedethosome, the method including: preparing an aqueous solution of a bioactive substance,preparing a lipid-dissolved solution by dissolving lipids in ethanol, preparing a hydrated liquid crystalline phase by hydrating the lipid-dissolved solution by mixing and agitating the bioactive substance aqueous solution together with the lipid-dissolved solution, and preparing an ethosome solution by adding purified water to the hydrated liquid crystalline phase to produce a mixture and agitating the mixture.