Five-membered heterocyclic amides wnt pathway inhibitor

摘要

Disclosed in the present invention is a five-membered heterocyclic amides Wnt pathway inhibitor, belonging to compounds that regulate the activities of a Wnt signaling pathway, and a method for preparing such compounds and use of such compounds in preparing drugs for antagonizing a Wnt signaling pathway are provided. The five-membered heterocyclic amides Wnt pathway inhibitor provided in the present invention has remarkable anti-tumor activities on the basis of a rational drug design for targets, and can be used in developing a new generation of Wnt pathway inhibitor, having a high clinical application value and a considerable market potential.