Disclosed is an Andrias davidianus cartilage preparation. The Andrias davidianus cartilage enzymatic extract of the present invention is obtained by the following method, comprising obtaining cartilage from Andrias davidianus, proteolyzing the obtained cartilage, obtaining a supernatant after the proteolysis, and drying the supernatant. The Andrias davidianus cartilage enzymatic extract and an alcohol-soluble component thereof of the present invention comprises a cartilage polypeptide and have effects of lowering uric acid or treating hyperuricemia.
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