DETECTION OF BIOLOGICAL CELLS AND TRACING OF CELL LINEAGE

摘要

The present disclosure relates to methods, systems and computer program products for detecting biological cells and/or tracing a cell lineage forest of biological cells. The tracing or detecting comprises obtaining multiple microscopy images, in particular lens-free microscopy images, depicting the biological cells. It further comprises generating a probability map for one of the microscopy images, the probability map indicating probabilities for the presence of the biological cells at multiple regions, in particular pixels, of the one microscopy image, and/or determining, based on multiple generated probability maps, one for each of the multiple microscopy images, a cell lineage forest indicating the descent and/or the localisation of at least some of the biological cells over the sequence of the multiple microscopy images.