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BIOINFORMATICS ANALYSIS METHOD AND SYSTEM FOR HPV PRECISE TYPING

机译:HPV精确分型的生物信息学分析方法及系统

摘要

Disclosed in the present invention are a bioinformatics analysis method and system for HPV precise typing. The method comprises: receiving sequencing fragments obtained through high-throughput sequencing technology to obtain a reads sequence of each sample; grouping and clustering the reads sequences of all samples, comparing and screening the clustered reads sequences with HPV reference sequences, and determining the matching results of the screened reads sequences; and carrying out HPV typing on the reads sequences of determined HPV types by using an LDA model and finally determining the HPV type of each reads sequence.
机译:本发明公开了一种用于HPV精确分型的生物信息学分析方法和系统。该方法包括:接收通过高通量测序技术获得的测序片段,以获得每个样品的阅读序列;对所有样本的阅读序列进行分组和聚类,将聚类阅读序列与HPV参考序列进行比较和筛选,并确定筛选出的阅读序列的匹配结果;然后使用LDA模型对确定的HPV类型的阅读序列进行HPV分类,最后确定每个阅读序列的HPV类型。

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