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COMBINATION THERAPY OF FRACTIONATED RADIATION AND SAPC-DOPS FOR THE TREATMENT OF TUMORS
COMBINATION THERAPY OF FRACTIONATED RADIATION AND SAPC-DOPS FOR THE TREATMENT OF TUMORS
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机译:放射治疗和SAPC-DOPS联合疗法治疗肿瘤
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摘要
Methods of treating a malignant solid tumor in a patient in need thereof are provided, the methods including administering to the patient a combination therapy comprising: fractionated radiation therapy and a therapeutically effective amount of saposin C (SapC) and dioleoylphosphatidylserine (SapC-DOPS), wherein the fractionated radiation therapy includes a plurality of radiation fractions, each of said fractions delivering a radiation dose lower than a dose effective to inhibit tumor growth when administered alone. Also provided are methods of enhancing anti-tumor efficacy of SapC-DOPS.
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