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TREM2 AGONISTS FOR THE STIMULATION OF MICROGLIA AND METHODS OF IDENTIFICATION
TREM2 AGONISTS FOR THE STIMULATION OF MICROGLIA AND METHODS OF IDENTIFICATION
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机译:用于刺激小胶质细胞的TREM2激动剂及其鉴定方法
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摘要
The present disclosure is directed to methods of promoting phagocytosis, particularly the phagocytic activity of microglia via activation of triggering receptor expressed on myeloid cells 2 (TREM2). The present disclosure is also directed to methods of activating TREM2 in a cell, particularly a neuronal cell exhibiting an accumulation of a pathogenic protein. The present disclosure is directed to detecting an effect of a compound on the TREM2 activity as well.
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