LEONURINE CRYSTAL AND USE THEREOF IN PREPARATION OF INSULIN SENSITIZER, HYPOGLYCEMIC DRUG AND LIPID-LOWERING DRUG

摘要

A crystalline structure of leonurine and use thereof in preparing drugs. Six crystals of leonurine sulfate having different structures, of which, two are hydrates, two are amorphous, one is a methanolate, and one is an ethanolate. The crystal forms of leonurine can be used to prepare an insulin sensitizer, a hypoglycemic drug and a lipid metabolism modulatory drug. The insulin sensitizer can be used to treat insulin resistance syndrome, and the lipid metabolism modulatory drug can be used to treat lipid metabolism disorders, hyperlipidemia and complications thereof.