首页> 外国专利> INHIBITORS OF CYCLIC-AMP RESPONSE ELEMENT-BINDING PROTEIN

INHIBITORS OF CYCLIC-AMP RESPONSE ELEMENT-BINDING PROTEIN

机译:环-AMP反应元件结合蛋白的抑制剂

摘要

The present disclosure provides compounds of Formula (I), and pharmaceutically acceptable salts thereof. The compounds described herein are useful in treating diseases associated with the binding of CREB to CREB-binding protein (CBP) and/or the CREB-CBP pathway, (e.g., proliferative diseases, for example, cancer (e.g., lung cancer or breast cancer), and inflammatory disease (e.g., pancreatic fibrosis or liver fibrosis)). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.
机译:本公开内容提供了式(I)的化合物及其药学上可接受的盐。本文所述的化合物可用于治疗与CREB与CREB结合蛋白(CBP)和/或CREB-CBP途径结合相关的疾病(例如, 。增生性疾病,例如癌症) (例如。,肺癌或乳腺癌)和炎症性疾病(例如,胰腺纤维化或肝纤维化)。本公开中还提供了药物组合物,试剂盒,方法和用途,包括或使用本文所述的化合物。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号