首页> 外国专利> COMPOSITION FOR TREATING A PATIENT WITH A RESPIRATORY DISEASE CAUSED BY CHRONIC INFLAMMATION, PRODUCTION METHOD, AND USE OF SAID COMPOSITION

COMPOSITION FOR TREATING A PATIENT WITH A RESPIRATORY DISEASE CAUSED BY CHRONIC INFLAMMATION, PRODUCTION METHOD, AND USE OF SAID COMPOSITION

机译:用于治疗由慢性炎症,生产方法和使用所述成分引起的呼吸系统疾病的患者的组合物

摘要

The invention relates to a composition for treating a patient with a respiratory disease caused by chronic inflammation, said composition comprising at least one DNAzyme that specifically down-regulates the expression of GATA-3 and/or at least one DNAzyme that specifically down-regulates the expression of Tbet. The composition is characterised in that the concentration of the DNAzyme in the composition is lower than 75 mg/ml. The invention also relates to a method for producing the composition according to the invention, and to a use of the composition as a medicament for treating a patient with a respiratory disease caused by chronic inflammation.
机译:本发明涉及一种用于治疗患有由慢性炎症引起的呼吸系统疾病的患者的组合物,所述组合物包含至少一种特异性下调GATA-3表达的DNA核酶和/或至少一种特异性下调GATA-3表达的DNA核酶。 Tbet的表达。该组合物的特征在于组合物中DNA核酶的浓度低于75mg / ml。本发明还涉及生产根据本发明的组合物的方法,并且涉及该组合物作为用于治疗患有由慢性炎症引起的呼吸系统疾病的患者的药物的用途。

著录项

  • 公开/公告号WO2019122267A1

    专利类型

  • 公开/公告日2019-06-27

    原文格式PDF

  • 申请/专利权人 STERNA BIOLOGICALS GMBH & CO. KG;RENZ JONAS;

    申请/专利号WO2018EP86438

  • 发明设计人 RENZ JONAS;

    申请日2018-12-20

  • 分类号A61P11;A61K9;A61K31/7088;C12N15/113;A61P29;A61P11/06;

  • 国家 WO

  • 入库时间 2022-08-21 11:54:13

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