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TWO-PHOTON FLUORESCENT COMPOUNDS FOR SPECIFIC LIPID DROPLET IMAGING IN LIVE CELLS AND DEEP TISSUES AT ULTRALOW CONCENTRATION
TWO-PHOTON FLUORESCENT COMPOUNDS FOR SPECIFIC LIPID DROPLET IMAGING IN LIVE CELLS AND DEEP TISSUES AT ULTRALOW CONCENTRATION
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机译:超低浓度活细胞和深层组织中特定脂质液滴成像的两光子荧光化合物
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摘要
Fluorescent compounds that have aggregation-induced emission (AIE) characteristics. The compounds can be utilized as lipid droplet (LD) -specific bio-probes in cell imaging, with high photostability and brightness. For example, the compounds can be used for specific two-photon LDs staining in live cells and deep-tissues at ultralow concentrations. The compounds exhibit a large Stokes shift (110 nm), high solid fluorescence quantum yields (up to 0.30), a good two-photon absorption cross-section (45-100 GM at 860 nm), high biocompatibility, and good photostability.
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