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DIAGNOSTIC AND PROGNOSTIC METHOD FOR MYELOFIBROSIS

机译:骨髓纤维化的诊断和预后方法

摘要

The present invention generally relates to a MPNs marker and particularly to a biomarker associated with MF. The present invention provides a method for diagnosis, prognosing or staging MPNs, in particular PMF, by measuring a specific marker. Accordingly, a first aspect of the present invention relates to an assay method for the detection and quantification of the levels of EDA FN in a biological sample. Moreover, a second aspect of the present invention relates to a method for diagnosis, prognosing or staging MF in a living subject based on the measured levels of EDA FN.
机译:本发明总体上涉及MPNs标记物,尤其涉及与MF相关的生物标记物。本发明提供了一种通过测量特定标志物来诊断,预后或分级MPN,特别是PMF的方法。因此,本发明的第一方面涉及一种用于检测和定量生物样品中的EDA FN水平的测定方法。此外,本发明的第二方面涉及一种用于基于测得的EDA FN水平在活体受试者中诊断,预后或分期MF的方法。

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