INJECTABLE COMPOSITION FOR CONTROLLED-RELEASE OF ACTIVE INGREDIENT TO MANAGE POSTOPERATIVE PAIN OR NEUROPATHIC BACK PAIN

摘要

Provided are an in situ forming implant formulation for controlled-release of a pharmaceutically active ingredient to manage pain including postoperative and neuropathic back pain and a method for managing pain using the formulation which comprises a biodegradable polymer and one or more active ingredients of analgesic agents to provide long-lasting pain relief for at least 7 or 9 days without the adverse effects from systemic administration.