首页> 外国专利> HETEROBIFUNCTIONAL COMPOUND HAVING MONODISPERSED POLYETHYLENE GLYCOL IN MAIN CHAIN OR SIDE CHAIN

HETEROBIFUNCTIONAL COMPOUND HAVING MONODISPERSED POLYETHYLENE GLYCOL IN MAIN CHAIN OR SIDE CHAIN

机译:主链或侧链中具有单分散性聚乙二醇的异功能化合物

摘要

The present invention is a heterobifunctional monodispersed polyethylene glycol represented by formula (1). (In the formula, each of X1 and Y1 represents an atomic group which contains a functional group that forms a covalent bond by reacting with a functional group that is present in a biologically functional molecule, and the functional group contained in X1 and the functional group contained in Y1 are different from each other; R1 represents a hydrocarbon group having 1-7 carbon atoms, or a hydrogen atom; n represents an integer of 3-72; l represents an integer of 2-72; A1 represents -L1-(CH2)m1- or -L1-(CH2)m1-L2-(CH2)m2-, wherein L1 represents a specific bond or a single bond, L2 represents a specific bond, and each of m1 and m2 independently represents an integer of 1-5; B1 represents -L3-(CH2)m3-, -L3-(CH2)m3-L4-(CH2)m4- or a single bond, wherein L3 represents an amide bond or a single bond, L4 represents a specific bond, and each of m3 and m4 independently represents an integer of 1-5; and C1 represents -L5-(CH2)m5-, -O-CH2- or a single bond, wherein L5 represents a specific bond or a single bond, and m5 represents an integer of 1-5.)
机译:本发明是由式(1)表示的杂双官能单分散聚乙二醇。 (式中,X 1 和Y 1 表示一个原子团,该原子团包含一个官能团,该官能团通过与存在于​​其中的官能团反应形成共价键生物功能分子,X 1 中包含的官能团和Y 1 中包含的官能团彼此不同; R 1 表示具有1-7个碳原子或氢原子的烃基; n表示3-72的整数; l表示2-72的整数; A 1 表示-L 1 -(CH 2 m1 -或-L 1 -(CH 2 m1 -L 2 -(CH 2 m2 -,其中L 1 代表特定键或单键,L 2 代表特定键,m1和m2各自独立地表示1-5的整数; B 1 代表-L 3 -(CH 2 m3 -,-L 3 -(CH 2 m3 -L 4 -(C H 2 m4 -或单键,其中L 3 代表酰胺键或单键,L 4 表示特定键,m3和m4分别独立地表示1〜5的整数。 C 1 表示-L 5 -(CH 2 m5 -,-O-CH 2 -或单键,其中L 5 表示特定键或单键,m5表示1-5的整数。)

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