COMPOSITIONS AND METHODS FOR ENFORCING FUCOSYLATION OF LACTOSAMINYL GLYCANS IN HUMAN CELLS WITH αALPHA(1,3)-FUCOSYLTRANSFERASES

摘要

The present disclosure provides, inter alia, compositions and methods for enforcing a pattern of cell surface fucosylated lactosaminyl glycans on a human cell. In certain embodiments, the compositions and/or methods utilize one or more members of the α(1,3)-fucosyltransferase family. In certain embodiments, a process for custom-modifying a fucosylated lactosaminyl glycan on a human cell is disclosed.