COMBINATION OF DODECANOIC ACID AND PROSTAGLANDIN E2 AS AUXILIARY DIAGNOSTIC MARKER OF MACROSOMIA AND APPLICATION THEREOF

摘要

Disclosed is a combination of dodecanoic acid and prostaglandin E2 acting as an auxiliary diagnostic marker of macrosomia and an application thereof, relating to the fields of analytical chemistry and clinical medicine, wherein the marker is metabolic small molecular dodecanoic acid and prostaglandin E2 of serum during pregnancy. The marker adopts the UPLC-Q exactive MS method for detection, has better sensitivity and specificity, and is capable of being used for the early diagnosis or monitoring of macrosomia, thereby having a better promotional value in clinical applications.