1 1 Once-daily fixed-dose combination bilayer tablet comprising cilostazol and angiotensin receptor blockers and manufacturing method thereof

摘要

The present invention relates to a once-daily once-daily complex double-layer tablet containing a fixed dose of cilostazol and an angiotensin receptor blocker, and a method for preparing the same, wherein the two-layer tablet according to the present invention comprises a release layer of cilostazol and an angiotensin receptor blocker Wherein the cilostazol emissive layer comprises a fixed amount of cilostazol and an angiotensin receptor blocker by the use of a specific fixed amount of povidone K-90 and Eudragit RL or RS as the parenteral release agent And it can be widely used as a combination preparation for elderly patients with frequent ischemic complex vascular diseases accompanied by hypertension and patients who are susceptible to diabetes, chronic cardiovascular diseases and kidney disease And the convenience of medication and patient compliance can be improved.