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Composition for Predicting Survival and the Response of a Patient with Myelodysplastic Syndromes to Hypomethylating Agent

机译:用于预测存活和骨髓增生异常综合征患者对次甲基化剂反应的组合物

摘要

The present invention relates to a composition, a gene panel and a kit for confirming the mutation of gene markers for prediction of survival prognosis and response to treatment of hypomethylated formulations in patients with myelodysplastic syndromes, responsiveness to hypomethylated formulations in patients with myelodysplastic syndromes And a method for providing information for predicting the survival prognosis. The composition for predicting the response and survival prognosis of a hypomethylated formulation of the present invention can provide a more accurate prediction of the prognosis than the existing composition and can provide useful information for determining the treatment direction of the patient with the myelodysplastic syndrome.
机译:本发明涉及用于确认基因标志物突变的组合物,基因组和试剂盒,用于预测骨髓增生异常综合症患者的存活预后和对低甲基化制剂的治疗的反应,对骨髓增生异常综合症患者对低甲基化制剂的响应性和提供用于预测生存预后的信息的方法。与现有的组合物相比,本发明的用于预测低甲基化制剂的反应和生存预后的组合物可以提供对预后的更准确的预测,并且可以提供用于确定患有骨髓增生异常综合症的患者的治疗方向的有用信息。

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