TROP2 - ANTI-TROP2 ANTIBODY-DRUG CONJUGATE

摘要

Providing anti-tumor efficacy and safety, and excellent anti-tumor efficacy. The following equation Positive antibody and an anti-TROP2 antibody represented by the following formula: -L ¹ -L ² -L ^P -NH- (CH ₂ ) n ¹ -L ^a - (CH ₂ ) n ² -C (= O) - (Wherein the anti-TROP2 antibody binds at the end of L ¹ , and the anti-tumor compound binds through the linker of the structure having the nitrogen atom of the amino group at the 1-position as a binding site, (CH ₂ ) n ² -C (= O) - moiety).