Crystalline forms of compounds inhibiting protein kinase activity and their applications

摘要

3-yl} -N- {4 - [((4-fluorophenyl) ethoxy] (3S, 5R) -3,5-dimethylpiperazinyl) carbonyl] phenyl} carboxamide hydrochloride) and a hydrate or solvate of the compound are provided. Methods of making such compounds and crystal forms, related intermediates, pharmaceutical compositions comprising such compounds, and uses of the compounds or crystal forms for the manufacture of pharmaceutical products for the treatment of diseases, conditions or disorders, , / RTI a symptom, or a disorder. Formula I