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Chimeric pig swine virus type 2 (PCV2) vaccine

机译:嵌合猪猪病毒2型(PCV2)疫苗

摘要

A vaccine composition and method for providing immunization against PCV2 genotypes, including by administration of a recombinant PCV2 capsid polypeptide comprising an antigenic epitope from a capsid of the multi-pig cotransvirus type 2 (PCV2) genotype is described. In another embodiment, a recombinant chimera for use as a vaccine for use as a vaccine, comprising a non-pathogenic backbone of porcine circovirus type 1 (PCV1) and a sequence encoding a PCV2 capsid polypeptide comprising an antigenic epitope from the capsid of multiple PCV2 genotypes, Pig serovirus is provided.
机译:描述了用于提供针对PCV2基因型的免疫的疫苗组合物和方法,包括通过施用重组PCV2衣壳多肽,所述重组PCV2衣壳多肽包含来自多猪共转化病毒2型(PCV2)基因型的衣壳的抗原表位。在另一个实施方案中,用作疫苗的重组嵌合体用作疫苗,其包含猪圆环病毒1型(PCV1)的非致病性骨架和编码包含来自多个PCV2的衣壳的抗原表位的PCV2衣壳多肽的序列基因型,提供猪血清病毒。

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