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Composition for Preventing or Treating Periodontal Disease Comprising Scutellaria Extract treated by Enzyme Isolated from Aspergillus niger as Active Ingredient
Composition for Preventing or Treating Periodontal Disease Comprising Scutellaria Extract treated by Enzyme Isolated from Aspergillus niger as Active Ingredient
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机译:用从黑曲霉分离的酶作为活性成分处理的黄S提取物的预防或治疗牙周病的组合物
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摘要
The present invention relates to a composition for preventing or treating a periodontal disease comprising a Scutellaria baicalensis extract treated by an enzyme derived from Aspergillus niger as an active ingredient. According to the present invention, the Scutellaria baicalensis extract treated by an enzyme derived from Aspergillus niger enhances mineralization of osteoblasts, promotes proliferation of periodontal ligament cells, and exhibits excellent activity in prevention or treatment of a periodontal disease by expression inhibition of interleukin-1β, tumor necrosis factor-alpha (TNF-α), and matrix metalloproteinase-1 (MMP-1). Therefore, the Scutellaria baicalensis extract can be effectively used for purposes such as a pharmaceutical composition or health functional food.
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