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A Composition for Cryopreservation of acellular dermal matrix and a Method for making the Same

机译:冷冻保存无细胞真皮基质的组合物及其制备方法

摘要

The present invention relates to a composition for cryopreservation of a cell-free dermis substrate, a method for producing a cryopreserved cell-free dermis substrate, and a cryopreserved cell-free dermis substrate produced by the method. The composition for cryopreservation of the present invention can maintain a fresh state without damaging the dermis skin during thawing after freezing, and exhibits an excellent preserving effect for cryopreservation for a long period of time. In addition, the cryopreserved cell-free dermis substrate produced according to the method of the present invention has a high tissue safety and can be effectively used a substitute for autotransplantation since an extracellular matrix structure and a basement membrane are maintained without damage.
机译:本发明涉及用于冷冻保存无细胞真皮基质的组合物,制备冷冻保存的无细胞真皮基质的方法以及通过该方法制备的冷冻保存的无细胞真皮基质。本发明的冷冻保存用组合物在冷冻后的解冻过程中可以保持新鲜状态而不会损害真皮层,并且对于长时间的冷冻保存具有优异的保存效果。另外,根据本发明的方法生产的冷冻保存的无细胞真皮基质具有高的组织安全性,并且由于保持了细胞外基质结构和基底膜无损伤,因此可以有效地用作自体移植的替代物。

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