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A drug conjugate with a self-stabilizing linker having improved physicochemical properties
A drug conjugate with a self-stabilizing linker having improved physicochemical properties
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机译:具有自稳定接头的药物偶联物,具有改善的理化性质
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摘要
Disclosed are compounds and compositions wherein the drug unit or moiety is linked to the targeted ligand unit via a self-stabilizing linker unit that is released at the targeted site of action. Methods of treating diseases characterized by targeted abnormal cells, such as cancer or autoimmune diseases, using the compounds and compositions of the present invention are also disclosed.
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