Deuterated 3- (4,5-Substituted Aminopyrimidine) Phenyl Derivatives and Their Applications

摘要

The present invention relates to deuterated 3- (4,5-substituted pyrimidinamine) phenyl derivatives of deuterated 3- (4,5-substituted aminopyrimidine) phenyl derivatives and their applications, Is a pharmaceutically acceptable salt thereof. The compounds or salts thereof can be used to treat or prevent diseases or conditions through epidermal growth factor receptors (EGFRs) in a specific mutant form, and effectively inhibit the growth of various tumor cells. It can also be used to produce antitumor drugs by showing inhibitory effects on EGFR, Her family, and other proteases.