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Treatment of severe atopic dermatitis by administration of IL-4R inhibitor

机译:给予IL-4R抑制剂治疗重症特应性皮炎

摘要

The present invention provides a method for the treatment of moderate to severe or severe atopic dermatitis (AD). The methods of the invention include administering to a subject in need thereof one or more doses of an interleukin-4 receptor (IL-4R) inhibitor such as an anti-IL-4R antibody. In certain embodiments, the methods of the invention are used to treat severe AD in patients where the disease is not controlled by systemic therapy (e. G., Cyclosporin A) or where such therapy can not be recommended.
机译:本发明提供了一种用于治疗中度至重度或重度的特应性皮炎(AD)的方法。本发明的方法包括给予有需要的受试者一剂或多剂白介素-4受体(IL-4R)抑制剂,例如抗IL-4R抗体。在某些实施方案中,本发明的方法用于治疗不能通过全身疗法(例如环孢菌素A)控制疾病或不能推荐这种疗法的患者中的严重AD。

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