首页> 外国专利> AO356 Lactobacillus paracasei AO356 strain with Anti-Obesity Ability and Composition for treatment or improvement or preventing of obesity comprising the same

AO356 Lactobacillus paracasei AO356 strain with Anti-Obesity Ability and Composition for treatment or improvement or preventing of obesity comprising the same

机译:具有抗肥胖能力的AO356副干酪乳杆菌AO356菌株和用于治疗或改善或预防肥胖症的组合物

摘要

A novel lactobacillus paracasei AO356 strain of the present invention is separated from a human body, thereby having excellent activity for alleviating, preventing or treating obesity by having high stability, exhibiting adipocyte differentiation suppression and differentiation inducing activity to M2 macrophage from M1 and M0 macrophages in vitro tests, and exhibiting weight loss activity and decrease in blood lipid level through browning of white fat in animal experiments. Therefore, the novel strain of the present invention has low possibility of side effects and can have a diet effect without controlling an amount of food intake, unlike conventional functional diet food or drugs which have a side effect problem, thereby being used for a pharmaceutical composition for treating or preventing obesity or a food composition for alleviating or preventing obesity.
机译:从人体内分离出本发明的新型副干酪乳杆菌AO356菌株,具有高稳定性,具有减轻,预防或治疗肥胖症的优异活性,对来自M1和M0巨噬细胞的M2巨噬细胞表现出脂肪细胞分化抑制和分化诱导活性。体外测试,并通过动物实验中的白色脂肪褐变表现出减肥活性和降低血脂水平。因此,与常规的功能性减肥食品或具有副作用问题的药物不同,本发明的新型菌株具有较低的副作用可能性,并且可以在不控制食物摄入量的情况下具有减肥作用,从而用于药物组合物。用于治疗或预防肥胖症的食品或用于减轻或预防肥胖症的食品组合物。

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