Composition for preventing ameliorating and treating inflammatory diseases comprising extract of undried immature astrigent persimmon of miyrangbansi as effective component

摘要

The present invention relates to a composition for preventing, ameliorating or treating inflammatory diseases, comprising an extract of unripe persimmon calyxes of flat Miryang persimmons harvested in Miryang as an active ingredient. The extract of unripe persimmon calyxes of flat Miryang persimmons harvested in Miryang, which is an active ingredient of the present invention, is highly effective in scavenging nitric oxide (NO), thereby exhibiting excellent anti-inflammation activities. According to results of comparing an extract of unripe persimmon calyxes of flat persimmons, an extract of ripe persimmon calyxes of flat persimmons, and an extract of persimmon calyxes of dried persimmons for each variety, harvested in Gojongsi in Hamyang, Dansung-si in Hamyang, Miryang, of dried persimmons, the extract of unripe persimmon calyxes of flat Miryang persimmons harvested in Miryang described as an active component in the present invention is further effective in scavenging NO. The extract of unripe persimmon calyxes of flat Miryang persimmons harvested in Miryang has no cytotoxicity, and thus has an effect of reducing ear edema caused by dermatitis. Accordingly, the extract can be effectively used as a pharmaceutical composition for anti-inflammation, a composition for a health functional food or a composition for a quasi-drug.