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Method for producing capsular polysaccharide protein conjugate derived from Streptococcus pneumoniae serotype 19F

机译：源自肺炎链球菌血清型19F的荚膜多糖蛋白缀合物的制备方法

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摘要

The present invention provides a method for producing a polysaccharide-protein conjugate using a capsular polysaccharide derived from Streptococcus pneumoniae serotype 19F conjugated to a transporter protein. The method includes an extended culture step prior to filtration to remove free polysaccharides.

机译：本发明提供了一种使用与转运蛋白缀合的来源于肺炎链球菌血清型19F的荚膜多糖生产多糖-蛋白缀合物的方法。该方法包括在过滤之前的延长的培养步骤，以去除游离多糖。 展开▼

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公开/公告号KR20190111952A

专利类型

公开/公告日2019-10-02

原文格式PDF

申请/专利权人 머크 샤프 앤드 돔 코포레이션;
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申请/专利号KR20197022152

发明设计人 윈터스 마이클 알버트;맥네이르 존 이.;
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申请日2018-01-30

分类号C07K14/34;A61K39;A61K39/09;A61K47/64;G01N33/569;

国家 KR

入库时间 2022-08-21 11:49:43

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1. 由肺炎链球菌血清型19F生产荚膜多糖蛋白缀合物的方法 [P] . 中国专利： CN110225757A . 2019-09-10

2. 从冻干球生产肺炎链球菌荚膜多糖载体蛋白缀合物的方法 [P] . 中国专利： CN112074294A . 2020-12-11

3. METHODS FOR PRODUCTION OF CAPSULAR POLYSACCHARIDE PROTEIN CONJUGATES FROM STREPTOCOCCUS PNEUMONIAE SEROTYPE 19F [P] . 美国专利： US2020222550A1 . 2020-07-16

机译：从19F型肺炎链球菌生产多糖多糖蛋白的方法

4. METHODS FOR PRODUCTION OF CAPSULAR POLYSACCHARIDE PROTEIN CONJUGATES FROM STREPTOCOCCUS PNEUMONIAE SEROTYPE 19F [P] . 欧洲知识产权局专利： EP3576759A1 . 2019-12-11

机译：从19F型肺炎链球菌生产多糖多糖蛋白的方法

5. METHODS FOR PRODUCTION OF CAPSULAR POLYSACCHARIDE PROTEIN CONJUGATES FROM STREPTOCOCCUS PNEUMONIAE SEROTYPE 19F [P] . 世界知识产权组织专利： WO2018144438A1 . 2018-08-09

机译：从19F型肺炎链球菌生产多糖多糖蛋白的方法

1. Impact of the Conjugation Method on the Immunogenicity of Streptococcus pneumoniae Serotype 19F Polysaccharide in Conjugate Vaccines [J] . Jan Poolman, Carl Frasch, Anu Nurkka, Clinical and vaccine immunology: CVI . 2011,第2期

2. Nuclear magnetic resonance assessment of controlled hydrolysis of the capsular polysaccharides of Streptococcus pneumoniae serotypes 19A and 19F [J] . Puyada Alain, Ojeda Gerardo M., Valdes Yury, Spectroscopy Letters . 2018,第1a5期

3. Investigation of Appropriate Cultivation Approach for Capsular Polysaccharide Production by Streptococcus pneumoniae Serotype 19F [J] . Mohsen Jalali, Shirin Tarahomjoo American Journal of Microbiological Research . 2015,第6期

4. COMPARISON OF CAPSULAR POLYSACCHARIDE CONFORMATIONS IN STREPTOCOCCUS AGALACTIAE SEROTYPE III AND STREPTOCOCCUS PNEUMONIAE SEROTYPE 14: IMPLICATIONS FOR IMMUNOGENICS. [C] . Michelle M. Kuttel, Neil Ravenscroft International Carbohydrate Symposium . 2018

5. The role of pneumococcal surface protein A in virulence of a capsular serotype 3 Streptococcus pneumoniae: Complement attack versus bacterial evasion. [D] . Ren, Bing. 2003

6. Impact of the Conjugation Method on the Immunogenicity of Streptococcus pneumoniae Serotype 19F Polysaccharide in Conjugate Vaccines [O] . Jan Poolman, Carl Frasch, Anu Nurkka, 2011

7. Impact of the Conjugation Method on the Immunogenicity of Streptococcus pneumoniae Serotype 19F Polysaccharide in Conjugate Vaccines ▿ [O] . Poolman, Jan, Frasch, Carl, Nurkka, Anu, 2010

8. Dendritic Cell-Derived Exosomes Express a Streptococcus pneumoniae Capsular Polysaccharide Type 14 Cross-Reactive Antigen That Induces Protective Immunoglobulin Responses against Pneumococcal Infection in Mice [R] . Colino, J., Snapper, C. M. 2007

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