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An anti-MERS-CoV monoclonal antibody and use of the same

机译:抗MERS-CoV单克隆抗体及其用途

摘要

The present invention relates to a monoclonal antibody that specifically recognizes a protein of MERS-coronavirus (MERS-CoV) or a portion of the protein, or a functional fragment thereof, and uses thereof, wherein the monoclonal antibody or functional fragment thereof comprises any one polypeptide sequence selected from the group consisting of the following polypeptide sequences: a heavy chain comprising a CDR1 region as depicted in SEQ ID NO: 1, a CDR2 region as depicted in SEQ ID NO: 2 and a CDR3 region as depicted in SEQ ID NO: 3; and a light chain comprising a CDR1 region as depicted in SEQ ID NO: 4, a CDR2 region as depicted in SEQ ID NO: 5 and a CDR3 region as depicted in SEQ ID NO: 6.
机译:本发明涉及特异性识别MERS冠状病毒的蛋白质(MERS-CoV)或其一部分或其功能片段的单克隆抗体及其用途,其中所述单克隆抗体或其功能片段包括任何一种。选自以下多肽序列的多肽序列:重链,其包含SEQ ID NO:1所示的CDR1区,SEQ ID NO:2所示的CDR2区和SEQ ID NO:2所示的CDR3区:3;轻链,其包含SEQ ID NO:4所示的CDR1区域,SEQ ID NO:5所示的CDR2区域和SEQ ID NO:6所示的CDR3区域。

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