Composition for diagnosing organ transplantation acute rejection comprising succinic acid and detection method using thereof

摘要

The present invention relates to a biomarker composition for the diagnosis of acute rejection of organ transplantation containing succinic acid as an active ingredient and a diagnostic method using the same. More particularly, the present invention relates to a biomarker composition for the diagnosis of acute rejection, As the concentration level increases, acute graft rejection appears, so that the level of succinic acid in the serum of a patient who has undergone organ transplantation can be provided as a biomarker for the diagnosis of acute rejection, and noninvasive in vitro diagnosis In this study, we evaluated the risk of acute graft rejection in patients with acute graft rejection by early diagnosis within 3 weeks.