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Anti-cancer drug Effective for Multidrug resistant cancer cells

机译:抗癌药对多药耐药癌细胞有效

摘要

The present invention relates to a PLGA nanoparticle loaded with dobutamine and a composition for preventing or treating cancer comprising the same. The PLGA nanoparticles loaded with dobutamine according to the present invention are in the form of a nano emulsion, which remarkably improves solubility and dispersibility in an aqueous solvent, and is excellent in the selective delivery efficiency to cancer cells. In addition, it can be used as a new therapeutic agent for cancer-resistant intractable cancer which has no distinct treatment method, while expanding the application of dobutamine as a cardiovascular treatment agent.
机译:本发明涉及负载有多巴酚丁胺的PLGA纳米颗粒和用于预防或治疗其的癌症组合物。根据本发明的负载有多巴酚丁胺的PLGA纳米颗粒为纳米乳液的形式,其显着提高了在水性溶剂中的溶解性和分散性,并且对癌细胞的选择性递送效率优异。此外,它可以用作没有独特治疗方法的抗癌性顽固性癌症的新治疗剂,同时扩大了多巴酚丁胺作为心血管治疗剂的应用。

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