首页> 外国专利> -1- SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONISTS METHODS OF PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT

-1- SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONISTS METHODS OF PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT

机译:-1-鞘氨醇-1-磷酸受体激动剂制备相同活性成分的药物和药物组合物的方法

摘要

The present invention relates to a novel compound according to formula (I), which is useful in the treatment of autoimmune disorders, and which is useful as a sphingosine-1-phosphate receptor agonist, a process for its preparation, a pharmaceutical composition containing the same as an active ingredient, The compounds according to the invention are effective against a wide range of autoimmune and chronic inflammatory diseases, including relapsing-remitting multiple sclerosis, and can also be used for the treatment or prevention of immunomodulatory disorders. [Chemical Formula 1] Wherein R1, R2, X, W, Q and S are as defined in the specification.
机译:本发明涉及根据式(I)的新型化合物,其可用于治疗自身免疫疾病,并且可用作鞘氨醇-1-磷酸受体激动剂,其制备方法,含有该化合物的药物组合物。与活性成分相同,本发明的化合物对多种自身免疫和慢性炎性疾病有效,包括复发-缓解型多发性硬化症,还可以用于治疗或预防免疫调节性疾病。 [化学式1]其中R1,R2,X,W,Q和S如说明书中所定义。

著录项

  • 公开/公告号KR101939657B1

    专利类型

  • 公开/公告日2019-01-17

    原文格式PDF

  • 申请/专利权人 주식회사 엘지화학;

    申请/专利号KR20140019113

  • 发明设计人 백승엽;이성배;박덕성;이원형;

    申请日2014-02-19

  • 分类号C07D413/04;A61K31/4245;A61P29;A61P37;

  • 国家 KR

  • 入库时间 2022-08-21 11:49:19

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