KRAS Pharmaceutical Composition Containing Nucleic Acid Targeting KRAS and Preparation Method of the Same

摘要

A nucleic acid targeting KRAS as an active ingredient; Cationic compounds; An amphiphilic block copolymer and a polylactic acid salt, wherein the KRAS-targeting nucleic acid forms a complex with the cationic lipid, and the complex is formed within the micelle structure formed by the amphiphilic block copolymer and the polylactic acid salt Wherein the KRAS-mediated pharmaceutical composition for nucleic acid delivery is provided.