Composition for preventing or treating inflammatory diseases or spinal cord injury comprising ursodeoxycholic acid

摘要

Ursodeoxycholic acid according to one aspect inhibits the secretion of inflammatory cytokines, inhibits the phosphorylation of ERK, JNK, or p38 in the MAPKs pathway, inhibits the phosphorylation of IκBα in the NF-κB pathway, Improving the motor function of the injured spinal cord, or repairing damaged spinal cord tissues, and thus can be usefully used in compositions for preventing, ameliorating, or treating inflammatory diseases or spinal cord injuries.