TIS21 Increasing red muscle mass through TIS21 gene expression

摘要

The present invention relates to a hypotensive method comprising the step of increasing the activity or expression of a TIS21 protein in a muscle or myoblast or a gene encoding said protein, wherein said TIS21 protein or a gene encoding said protein maintains or maintains expression of TIS21 But inhibition of TIS21 expression reduces myosin heavy chain (MyHC) type I protein. However, it has been confirmed that the amount of MyHC type Ι protein is increased in the myoblast overexpressing the TIS21 gene. Accordingly, it is possible to provide a composition for improving muscle development comprising the TIS21 protein or an expression regulator thereof as an active ingredient, It can be used as a feed composition.