TDP-43 TDP-43 SPECIFIC BINDING MOLECULES

摘要

There is provided a novel TDP-43-specific binding molecule comprising polypeptides such as human antibodies as well as fragments, derivatives and variants thereof. Methods are also provided for these TDP-43 specific binding molecules. Assays, kits and solid supports relating to TDP-43-specific binding molecules comprising polypeptides such as human antibodies are also disclosed. TDP-43-specific binding molecules, antibodies, immunoglobulin chain (s) as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for TDP-43 targeted immunotherapy and diagnosis, respectively have.