SIRT SIRT TREATMENT OF SIRTUIN SIRT RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A SIRTUIN SIRT

摘要

The present invention relates in particular to antisense oligonucleotides that modulate the expression and / or function of sirtuin (SIRT) by targeting natural antisense polynucleotides of sirtuin (SIRT). The invention also relates to the identification of these antisense oligonucleotides and their use in the treatment of diseases and disorders associated with the expression of sirtuin (SIRT).