CAPSULE FORMULATION COMPRISING MONTELUKAST OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND LEVOCETIRIZINE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

摘要

The present invention relates to a pharmaceutical composition comprising 1) a montelukast independent layer comprising montelukast or a pharmaceutically acceptable salt thereof; And 2) a levocetirizine-independent layer comprising levocetirizine or a pharmaceutically acceptable salt thereof in a separate state, and a method for producing the capsule preparation for preventing or treating allergic rhinitis and asthma. The capsule preparation according to the present invention can completely isolate the two active ingredients, minimizing the reactivity between the active ingredients, so that the stability of the product according to the change with time is excellent and the therapeutic effect can be maximized.