首页>
外国专利>
PAA-APBA PAA-APBA coated liquid crystal microdroplet manufacturing method thereof and non enzyme-based glucose biosensor using the same
PAA-APBA PAA-APBA coated liquid crystal microdroplet manufacturing method thereof and non enzyme-based glucose biosensor using the same
展开▼
机译:PAA-APBA涂布PAA-APBA的液晶微滴的制造方法以及使用其的非酶系葡萄糖生物传感器
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to liquid crystal microdroplets coated with PAA-APBA, a preparation method thereof, and a non-enzyme-based glucose biosensor using the same, including liquid crystal monomers in the form of droplets; A liquid crystal copolymer coated on a surface of the liquid crystal monomer and represented by the following Chemical Formula 1; And forming a covalent bond with the liquid crystal copolymer, and aminophenylboronic acid represented by the following Chemical Formula 2, to provide a liquid crystal micro droplet. [Formula 1] In Formula 1, n is an integer of 1 to 2000, m is an integer of 1 to 2000, p is an integer of 1 to 50, R 1 is -COO-R 5 , -C (CH 3 ) 2 Ph or -CH (CH 3 ) Ph, R 5 is a hydrogen atom, a straight alkyl group having 1 to 6 carbon atoms or a crushed alkyl group having 3 to 6 carbon atoms, R 2 is an aromatic hydrocarbon having 6 to 10 carbon atoms, R 3 is or , A is an alkyl group having 1 to 3 carbon atoms, R 4 is -CN or -R 6 -CN, R 6 is a straight alkyl group having 1 to 6 carbon atoms, a ground alkyl group having 3 to 6 carbon atoms, 5 to 6 carbon atoms Phosphorus cyclic alkyl group or aromatic hydrocarbon having 6 to 10 carbon atoms.) [Formula 2] Biosensor for non-enzymatic glucose measurement using liquid crystal microdroplets according to the present invention has the advantage that the liquid crystal-based biosensor, the manufacturing process is simple, the time required for manufacturing is relatively small. In addition, by using a polarizing optical microscope it can be easily confirmed whether the detection of glucose, has a relatively low detection limit of glucose of 0.05 mM, it is maintained stably up to about 1 month after manufacture, and shows a very excellent selectivity to glucose.
展开▼