首页> 外国专利> LRRK2 2- -3- 2-PHENYL OR PYRID-3-YL AMINOPYRIMIDINE DERIVATIVES AS KINASE LRRK2 MODULATORS FOR THE TREATMENT OF PARKINSON'S DISEASE

LRRK2 2- -3- 2-PHENYL OR PYRID-3-YL AMINOPYRIMIDINE DERIVATIVES AS KINASE LRRK2 MODULATORS FOR THE TREATMENT OF PARKINSON'S DISEASE

机译:LRRK2 2- -3- 2-苯基或吡啶-3-基氨基嘧啶衍生物作为激酶LRRK2调节剂,用于治疗帕金森氏病

摘要

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof: [Formula I] Where m, n, X, R 1 , R 2 , R 3 , R 4 and R 5 are as defined herein. The present invention also discloses methods and uses for the preparation of compounds for the treatment of diseases associated with the LRRK2 receptor, such as Parkinson's disease.
机译:本发明涉及式(I)的化合物或其药学上可接受的盐:[式I]其中m,n,X,R 1 ,R 2 , R 3 ,R 4 和R 5 如本文所定义。本发明还公开了用于制备化合物的方法和用途,所述化合物用于治疗与LRRK2受体相关的疾病,例如帕金森氏病。

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