首页> 外国专利> Telomere regulator genes in low-dose-rate irradiated EL4 cells and their detecting method

Telomere regulator genes in low-dose-rate irradiated EL4 cells and their detecting method

机译:低剂量辐照的EL4细胞端粒调控基因及其检测方法

摘要

The present invention relates to a method for detecting a group of telomeres regulatory genes in response to low dose rate low level radiation, and more specifically, after irradiation with low dose low level radiation to murine thymic lymphoma cells, the expression levels of the telomeres regulated genes are measured, and the common or The present invention relates to a method for detecting a telomere regulatory gene expressed alone. According to the present invention as described above, by providing a method for detecting a group of telomeres control genes in response to low dose rate low-level radiation, it can be utilized as a low-level radiation telomeres control gene that can evaluate the correlation between radiation exposure and carcinogenesis of industrial and medical workers In addition, it can be used as a low level telomeres regulatory genes for evaluating cancer progression and treatment of cancer patients as well as a low level telomeres gene recovery index for evaluating the causal relationship between radiation and cancer.
机译:本发明涉及一种响应低剂量率低水平辐射检测一组端粒调节基因的方法,更具体地讲,在用低剂量低水平辐射照射鼠胸腺淋巴瘤细胞后,调节端粒的表达水平本发明涉及检测单独表达的端粒调节基因的方法。如上所述,根据本发明,通过提供一种响应低剂量率低水平辐射检测一组端粒控制基因的方法,其可以用作可以评估相关性的低水平辐射端粒控制基因。辐射暴露与工业和医务工作者的癌变之间的关系此外,它还可以用作评估癌症进展和癌症患者治疗的低水平端粒调节基因,以及低水平端粒基因恢复指数以评估辐射之间的因果关系和癌症。

著录项

  • 公开/公告号KR102034828B1

    专利类型

  • 公开/公告日2019-11-08

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20170124184

  • 申请日2017-09-26

  • 分类号C12Q1/68;G01N33/574;

  • 国家 KR

  • 入库时间 2022-08-21 11:47:30

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