Contig Profile Update Method and Contig Formation Method for shotgun sequencing or transcriptome assembly

摘要

The present invention provides a method for updating a contiguous profile for DNA shotgun sequencing or RNA transcript assembly that enables correction of read errors to improve the performance of whole genome or whole transcriptome assembly. And a method for forming a contig, wherein each contig is represented by a consensus matrix of 4xN or Nx4 and a representative sequence of length N so as to align reads with the contigs. This is to improve efficiency and performance in performing the entire transcriptome assembly.