首页> 外国专利> IMPROVED AMINO ACID SEQUENCES ARE DIRECTED AGAINST THE RESEARCH-APPROXATING SURVEY OF THE HUMAN VIRUS (HRSV), AND POLYPEPTIDES, INCLUDING SUCH SEQUENCES, FOR PREVENTION AND AREA POLYPEPTIDES, INCLUDING SUCH SEQUENCES, FOR PREVENTION AND APPLIED POLYPEPTIDES, INCLUDING SUCH SEQUENCES, FOR PREVENTION AND APPLIED POLYPEPTIDES, INCLUDING SUCH SEQUENCES FOR PREVENTION, FOR PROFLACTICA / a / a / a / a / a / a / a, a / a / a / a / a / a / a / a / a, including such sequences, for prophylaxis of human sequences (HRSV), for the prophylaxis of human peptides

IMPROVED AMINO ACID SEQUENCES ARE DIRECTED AGAINST THE RESEARCH-APPROXATING SURVEY OF THE HUMAN VIRUS (HRSV), AND POLYPEPTIDES, INCLUDING SUCH SEQUENCES, FOR PREVENTION AND AREA POLYPEPTIDES, INCLUDING SUCH SEQUENCES, FOR PREVENTION AND APPLIED POLYPEPTIDES, INCLUDING SUCH SEQUENCES, FOR PREVENTION AND APPLIED POLYPEPTIDES, INCLUDING SUCH SEQUENCES FOR PREVENTION, FOR PROFLACTICA / a / a / a / a / a / a / a, a / a / a / a / a / a / a / a / a, including such sequences, for prophylaxis of human sequences (HRSV), for the prophylaxis of human peptides

机译:根据人类病毒(HRSV)和多肽的研究辅助调查结果,氨基酸序列得到了改进,其中包括预防和区域多肽的序列,包括在预防,预防和应用中的序列,在序列中进行预防和应用适用的多肽,包括预防用的此类序列/ a / a / a / a / a / a / a / a / a,a / a / a / a / a / a / a / a / a / a,包括此类序列,用于预防序列(HRSV),用于预防人类多肽

摘要

Amino acid sequences are provided that are directed against/and or that can specifically bind protein F of hRSV, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The amino acid sequences, polypeptides and therapeutic compounds and compositions provided by the invention show an improved stability, less immunogenicity and/or improved affinity and/or avidity for protein F of hRSV. The invention also relates to the uses of such amino acid sequences, polypeptides, compounds or constructs for prophylactic and/or therapeutic purposes.
机译:提供了针对/和/或可以特异性结合hRSV的蛋白F的氨基酸序列,以及包含或基本上由一种或多种此类氨基酸序列组成的化合物或构建体,尤其是蛋白质和多肽。本发明提供的氨基酸序列,多肽以及治疗性化合物和组合物显示出对hRSV的蛋白F的改善的稳定性,较低的免疫原性和/或改善的亲和力和/或亲和力。本发明还涉及此类氨基酸序列,多肽,化合物或构建体用于预防和/或治疗目的的用途。

著录项

  • 公开/公告号RU2016103067A3

    专利类型

  • 公开/公告日2019-08-08

    原文格式PDF

  • 申请/专利权人

    申请/专利号RU20160103067

  • 发明设计人

    申请日0000-00-00

  • 分类号C07K16/10;

  • 国家 RU

  • 入库时间 2022-08-21 11:47:15

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号