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METHOD FOR OBTAINING AN AGENT FOR BLOCKING EXPERIMENTAL PARKINSONISM
METHOD FOR OBTAINING AN AGENT FOR BLOCKING EXPERIMENTAL PARKINSONISM
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机译:获得阻止实验性帕金森病的代理商的方法
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摘要
FIELD: pharmaceuticals.SUBSTANCE: invention relates to pharmaceutical industry, namely to a method for obtaining an agent for blocking experimental parkinsonism. Method for obtaining an agent for blocking experimental parkinsonism comprises the preparation of a homogenized crude biomass of darkling beetles Alphitobius diaperinus bodies, homogenized biomass of darkling beetles Alphitobius diaperinus bodies is further subjected to aqueous extraction in two stages: at the first stage, one part of the darkling beetles Alphitobius diaperinus bodies is filled with distilled water, infused, centrifuged, and the centrate is separated; at the second stage, the resulting precipitate is filled with distilled water, infused, centrifuged, the centrate is separated, the obtained centrates are combined, the combined centrate is passed through a Millipore bacterial filter, and an aqueous extract of the darkling beetles Alphitobius diaperinus bodies is obtained, wherein the extract comprises: uracil, thymine, isoleucine, proline, phenylalanine, eumelanin, and immobilization is carried out by applying the aqueous extract to the ground sterile phyto-carrier until a moisture content of not more than 12 wt% is achieved.EFFECT: above-described method provides increased effectiveness of the agent.1 cl, 3 tbl, 1 ex
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机译:技术领域本发明涉及制药工业,即涉及一种获得用于阻断实验性帕金森病的药物的方法。获得用于阻断实验性帕金森病的药物的方法包括制备均化的黑甲虫Alphitobius diaperinus体的粗制生物质,再将黑化甲虫Alphitobius diaperinus体的均质的生物质分两个阶段进行水提取:在第一阶段,一部分将黑暗的甲虫Alphitobius diaperinus尸体充满蒸馏水,注入,离心并分离出浓缩物。在第二阶段,将所得沉淀物充满蒸馏水,注入,离心,分离浓缩物,合并获得的浓缩物,使合并的浓缩物通过密理博细菌过滤器,并使黑甲虫的水提取物Alphitobius diaperinus获得了其中的提取物,其中提取物包含:尿嘧啶,胸腺嘧啶,异亮氨酸,脯氨酸,苯丙氨酸,双榄精,并通过将含水提取物施用于研磨的无菌植物载体上进行固定,直到水分含量不超过12 wt%。效果:上述方法提高了药剂的效力.1 cl,3 tbl,1 ex
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