首页> 外国专利> METHOD FOR PREDICTING RISK OF DEVELOPMENT OF VENTRICULAR PREMATURE BEATS IN SCHOOLCHILDREN BEFORE PARTICIPATING IN SPORTS ACTIVITIES

METHOD FOR PREDICTING RISK OF DEVELOPMENT OF VENTRICULAR PREMATURE BEATS IN SCHOOLCHILDREN BEFORE PARTICIPATING IN SPORTS ACTIVITIES

机译:参加体育活动之前预测小学生室性早熟的发展的方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to the field of medicine, namely to pediatric cardiology, and relates to a method for predicting the risk of ventricular premature beats in schoolchildren before playing sports. Essence of the method: in schoolchildren, 1 month before the start of sports activities, a study of blood serum is carried out and the concentration of immunochemical parameters in it is determined: tumor necrosis factor-α, interleukin-10 and immunoglobulin G class autoantibodies to soluble cardiomyocyte antigen -COS-05. Further, a high risk of ventricular premature beats is predicted at a concentration of tumor necrosis factor-α from 11.5 to 13.5 pg/ml, at a concentration of interleukin-10 from 18.4 to 20.2 pg/ml and at a concentration of immunoglobulin G autoantibodies to soluble cardiomyocyte antigen -COS-05 from 9.8 to 12.3 standard units. And a low risk of ventricular premature beats is predicted at a concentration of tumor necrosis factor-α from 7.7 to 10.1 pg/ml, when the concentration of interleukin-10 is from 13.5 to 16.3 pg/ml, and when the concentration of immunoglobulin G class autoantibodies to soluble cardiomyocyte antigen -COS-05 is from 6.7 to 8.7 standard units.;EFFECT: proposed invention is aimed at improving the accuracy of predicting the risk of developing ventricular premature beats in children before playing sports.;1 cl, 1 tbl, 4 ex
机译:技术领域本发明涉及医学领域,即小儿心脏病学,并且涉及一种在运动前预测小学生心室早搏风险的方法。方法的实质:在运动开始前一个月的小学生中,对血清进行研究并确定其中的免疫化学参数浓度:肿瘤坏死因子-α,白介素-10和免疫球蛋白G类自身抗体可溶性心肌细胞抗原-COS-05。此外,预计在肿瘤坏死因子-α浓度为11.5至13.5 pg / ml,白介素10浓度为18.4至20.2 pg / ml以及免疫球蛋白G自身抗体浓度时,发生室性早搏的风险较高。从9.8到12.3标准单位的可溶性心肌细胞抗原-COS-05。当白细胞介素10的浓度为13.5 pg / ml且免疫球蛋白G的浓度为13.5 pg / ml时,肿瘤坏死因子-α的浓度为7.7至10.1 pg / ml时,室性早搏的风险较低。可溶性心肌细胞抗原-COS-05的一类自身抗体为6.7至8.7标准单位。效果:本发明旨在提高预测儿童运动前发生室性早搏风险的准确性。1cl,1 tbl ,4前

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