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ANTITUMOUR DRUG CONTAINING ANTITUMOUR PLATINUM COMPLEX, AND ANTITUMOUR EFFECT ENHANCER
ANTITUMOUR DRUG CONTAINING ANTITUMOUR PLATINUM COMPLEX, AND ANTITUMOUR EFFECT ENHANCER
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机译:包含抗铂复合物的抗肿瘤药和抗癌效果增强剂
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摘要
FIELD: medicine; pharmaceuticals.;SUBSTANCE: group of inventions relates to the chemical and pharmaceutical industry and is a method of enhancing the antitumour effect of an antitumour platinum complex and methods for treating a tumour, comprising: administering an antitumour platinum complex and a combination drug containing trifluridine and tipiracil hydrochloride in a molar ratio of 1:0.5, in combination to a mammal, where the daily dose of the combined drug on the day of administration of the combination drug is 50–100 % of the recommended dose of the combination drug for use in monotherapy and the daily dose of the antitumour platinum complex on the day of the administration of the antitumour platinum complex is 50–100 % of the recommended dose of the antitumour platinum complex for use in monotherapy, where the antitumour platinum complex is cisplatin, carboplatin or oxaliplatin, and where the malignant tumour being treated is a malignant tumour of the digestive system or lung cancer.;EFFECT: group of inventions describes new methods of treating malignant tumours with the use of a combination drug, which to a large extent has excellent antitumour effects with fewer side effects.;8 cl, 14 dwg, 7 tbl, 3 ex
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机译:领域:医学;物质:一组发明涉及化学和制药工业,并且是一种增强抗肿瘤铂复合物的抗肿瘤作用的方法和治疗肿瘤的方法,其包括:施用抗肿瘤铂复合物和含有三氟吡啶和与哺乳动物的摩尔比为1:0.5的盐酸替吡酯,在联合用药当天,联合用药的日剂量为推荐剂量的联合用药推荐剂量的50–100%单药治疗和抗肿瘤铂复合物给药当天的每日剂量是推荐用于单药治疗的抗肿瘤铂复合物推荐剂量的50–100%,其中抗肿瘤铂复合物为顺铂,卡铂或奥沙利铂,所治疗的恶性肿瘤是消化系统或肺癌的恶性肿瘤。一项发明描述了使用联合药物治疗恶性肿瘤的新方法,该药物在很大程度上具有优异的抗肿瘤作用且副作用较少。; 8 cl,14 dwg,7 tbl,3 ex
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